Jianhui Zhong Professor of Radiology (and Physics) Biological Physics office: phone: Medical Center 3-5313, P.O. Box 648 (585) 273-4518 fax: email: (585) 273-1033 jianhui.zhong@rochester.edu home page: http://www.bme.rochester.edu/bmeweb/faculty/zhong.html

Biographical Sketch

Prof. Zhong received his B.S. in Physics from Nanjing University, China, in 1982. He pursued his graduate study in experimental condensed matter physics at Brown University, receiving his Ph.D. in 1988. Prof. Zhong then went to the Yale University School of Medicine as a post-doctoral fellow in the emerging field of medical Magnetic Resonance Imaging (MRI), and joined the Yale faculty first as an Assist. Prof. in 1991, and then as an Assoc. Prof. in 1997. Prof. Zhong joined the University of Rochester in 1997. He was promoted to Professor of Radiology, Physics, and Biomedical Engineering in 2004. He currently serves as Associate Director of the MRI Resarch Group at the University Medical Center. Prof. Zhong has also been a visiting professor in several institutes, including the Chinese Science Academy, Tsinghua University, and Xiamen University, and has been serving on the Editorial Board of Magnetic Resonance Imaging since 2001. He has received Dean's Research Award from the Yale School of Medicine in 1996, and a URMC Reserach Excellence Award in 2004.

Research

Prof. Zhong's research activities, within the field of Biological Physics, involve studies of MRI signal changes in complex biological systems related to underlying physical processes such as molecular diffusion and variation of magnetic susceptibility. He is also involved in the development of novel MRI techniques. Understanding some of the important physical and physiological properties of biological tissues has led to new methods for the early detection of acute stroke, and to the development of brain functional MRI (fMRI). The experimental techniques used in Prof. Zhong's group include imaging in phantoms, extracted tissues, live animals, and humans, as well as computer simulations of magnetization in the heterogeneous environments that resembles tissues, and advanced imaging processing and statistical analysis.

Prof. Zhong's recent works include: modeling of reduced diffusion in brain ischemia; diffusion-weighted MRI for detection of neuronal electrical activities and status epilepticus; quantitative measurements of tumor oxygenation and flow; and development of intermolecular multiple-quantum coherence (iMQC) MRI.

Recent Publications

1. A simulation algorithm based on Bloch equations and product operator matrix: application to dipolar and scalar couplings
   C. Cai, Z. Chen, S. Cai, J. Zhong
   J. Magn. Reson 172, 242-253 (2005)
   
   
2. Finite difference simulation of diffusion behaviors under inter- and intra-molecular multiple-quantum coherences in liquid NMR
   Congbo Cai, Zhong Chen, Shuhui Cai, Xiaoqin Zhu, Jianhui Zhong
   Chemical Physics Letters 407, 438-443 (2005)
   
   
3. Selection of intra- or inter-molecular multiple-quantum coherences in NMR of highly polarized solution
   Zhu XQ, Chen Z, Cai SH, Zhong JH
   Physica B 362 (1-4), 286=294 (2005)
   
   
4. Theoretical formalism and experimental verification of lineshapes of NMR intermolecular multiple-quantum coherences spectra
   Bingwen Zheng, Zhong Chen, Shuhui Cai, Jianhui Zhong, Chaohui Ye
   J. Chem. Phys. 123, 74317 (2005)
   
   
5. Valproic Acid Adjunctive Therapy for HIV-Associated Cognitive Impairment: a First Report
   G. Schifitto, D. R. Peterson, J. Zhong, H. Ni, K. Cruttenden, M. Gaugh, H. E. Gendelman, M. Boska, H. Gelbard
   Neutology 66, 919-921 (2006)
   
   

For further details, go to Prof. Zhong's home page at: http://www.bme.rochester.edu/bmeweb/faculty/zhong.html

Go to Faculty Directory *